Background and aim: Diabetic retinopathy(DR) is one of ORG PITTED DATES the most common complications of long-standing diabetes mellitus(DM).Early detection of this complication in the preclinical stages by Visual Evoked Potential (VEP) may help formulate management strategies to preserve Vision.With this background in mind, we conducted a cross-se
Abstract Recently, neoadjuvant short-course radiation therapy (SCRT) has emerged as a valid treatment option for patients with locally advanced rectal cancer (LARC).We assessed SCRT plans using volumetric-modulated arc therapy (VMAT) with Halcyon and Infinity medical linear accelerators (Linacs) and compared the plan quality and delivery efficiency
Abstract The NASA human system risk board (HSRB) has long focused on trauma and acute medical illness as a key contributor to high level in-flight medical risk.However, ocular issues, trauma, and complaints during spaceflight are poorly characterized.In a retrospective case series, the NASA Brynaman RFC data from the life sciences data archieve (LS
The VH6-1 class of antibodies includes some of the broadest and most potent antibodies that neutralize influenza A virus.Here, we elicit and isolate anti-idiotype antibodies against germline versions of VH6-1 antibodies, use these to sort human leukocytes, and isolate a new VH6-1-class member, antibody L5A7, which potently neutralized diverse group
Axon degeneration is a tightly Chairs regulated, self-destructive program that is a critical feature of many neurodegenerative diseases, but the molecular mechanisms regulating this program remain poorly understood.Here, we identify S-phase kinase-associated protein 1A (Skp1a), a core component of a Skp/Cullin/F-box (SCF)-type E3 ubiquitin ligase c